The renewable starting point.
From a routine blood draw to living, donor-specific human tissue. Induced pluripotent stem cell lines are the foundation every other pillar is built on.
From a routine blood draw.
What reprogramming is
In plain terms: a mature cell taken from a donor is returned to a pluripotent state, able to become any tissue type in the body. The technique is well established in the field and has been since the original transcription-factor work, which is why it is the right foundation to build on rather than the thing we are trying to prove.
How a line is made
Blood cells from a routine draw are reprogrammed, expanded and characterised: pluripotency verification, karyotype, identity and sterility checks. Each donor is banked as at least three independent clones, and only lines that pass are banked.
Why banking matters
A biopsy is finite. A characterised, cryobanked line is not. Every experiment downstream can be repeated from the same starting point years later, which is what makes results comparable across time and across tissues.
What it enables
The same line differentiates into neural and hepatic tissue, so a brain organoid and a liver organoid can share a genome. That pairing is the platform's real advantage.
iPSC derivation, characterisation and cryobanking are standard practice in the field.
Our internal QC standards and banking workflow.
Reprogramming at a scale where genome-linked cohorts, not single lines, are the unit of work.