Platform

Four pillars, one starting point.

One donor, one genome, one renewable cell line, and more than one tissue built from it. The platform is organised so that everything downstream traces back to a single characterised starting point.

01

iPSC Reprogramming

The renewable starting point.

Donor-derived linesBlood-derivedQC & karyotype
02

Brain Organoids

Neural modelling toward repair.

NeurodegenerationNeurodevelopmentNeurotoxicity
03

Liver Organoids

Hepatic modelling toward therapy.

MetabolismToxicologyPatient-matched
04

Mitochondrial Therapy

Restoring cellular energy.

Transfer & transplantRespiration assaysAgeing biology
A robotic arm holding a shallow culture dish in a darkened instrument bay, a small translucent form glowing cyan and rose at its centre.
Formation · takwīn

One line. Many tissues.

Brain + liver: one donor, two organs.

The toxicity loop
  1. Input
    Compound
  2. Liver organoid
    Metabolism

    Many drugs are transformed in the liver before they act.

  3. Intermediate
    Active metabolite
  4. Brain organoid
    Efficacy + neurotoxicity

    Response on the donor's own genetic background.

  5. Output
    Readout

Testing the compound the body actually sees – one donor, two organs, one genetic background.

In development.

From preserved cells to living tissue.

Translational pathway

Preserve

Governed biological material with linked genomic and clinical data.

Reprogram

Donor-derived iPSC lines, characterised and banked.

Engineer

Bioreactor and scaffold conditions tuned for reproducibility.

Differentiate

Brain and liver organoids from the same genome.

Translate

Phenotyping, data integration and a route to therapy.

One donor
Preserved material
One genome
Linked sequence data
One iPSC line
Renewable, banked
Many organoids
Brain · liver · beyond
Programme status →